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Tablet coating defects |
Remedies |
Peelings
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- Erosion of core tablets, high friability and hygroscopic ingredients.
- If film coating formulation is poor.
- Tablets are too wet.
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- Improve core strength, reduce friability, take care of hygroscopic ingredients.
- Use DLPL tablet coating material.
- Adjust temperature to a bit higher with regular spray rate.
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Film cracking
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- Excess heating of tablet core.
- Film coating with less mechanical strength.
- Plasticizer content in coating material is too low.
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- Avoid high bed temperature.
- Use DLPL tablet coating material.
- Increase plasticizer concentration/use DLPL tablet coating material.
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Picking & sticking
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- Spray rate is high/uneven.
- Solid concentration is low.
- Drying air volume & temperature is low.
- Slow pan speed and inadequate load.
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- Adjust spray rate.
- Use DLPL coating material.
- Adjust gun to bed distance, increase airflow and temperature.
- Apply proper loading & increase pan speed.
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Orange Peel
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- High spray rate.
- High solid concentration in coating material.
- Coating solution is too viscous.
- Too low air pressure.
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- Decrease rate of spray.
- Use customised product from DLPL.
- Use low viscosity product from DLPL.
- Increase air pressure & optimise.
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Twinning
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- Tablet surface is flat.
- High spray rate.
- Low pan speed & air pressure.
- Spraying gun distance is not proper.
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- Better to change tablet shape., if possible.
- Reduce spray rate.
- Increase pan speed & atomization air pressure.
- Set gun to bed distance properly.
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Logo bridging
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- Plasticizer content is too low.
- Low inlet temperature/air pressure.
- High spray rate.
- Coating with low adhesion.
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- Use customised product from DLPL.
- Increase inlet temperature/air pressure.
- Reduce rate of spray.
- Choose high adhesion product from DLPL.
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Surface erosion
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- Tablet core friability is high
- Film strength is low
- High pan speed.
- Low spray rate.
- Hygroscopic ingredients
- Low solid concentration material.
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- Optimise core friability.
- Use customised product from DLPL.
- Reduce pan speed.
- Increase rate of spray.
- Reduce hygroscopic material.
- Use customised product from DLPL.
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